Control of Ca2+ influx and calmodulin activation by SK-channels in dendritic spines (dataset)

A 3-dimensional model of Ca2+ and calmodulin dynamics within an idealised, but biophysically-plausible, dendritic spine, demonstrates that SK-channels regulate calmodulin activation specifically during neurone firing patterns associated with induction of spike timing-dependent plasticity.

Creator(s) Griffith, Thom; Tsaneva-Atanasova, Krasimira; Mellor, Jack
Funder Engineering and Physical Sciences Research Council ; Biotechnology and Biological Sciences Research Council ; Wellcome Trust
Publisher University of Exeter
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