Bariatric Surgery in Morbidly Obese Insulin Resistant Humans Normalises Insulin Signalling but Not Insulin-Stimulated Glucose Disposal

Our data show that although Akt activity substantially improved after surgery, it did not lead to a full restoration of insulin-stimulated glucose disposal. This suggests that a major defect downstream of, or parallel to, Akt signalling remains after significant weight-loss.

Creator(s) Mimi Chen
Funder Medical Research Council, Diabetes Research and Wellness Foundation, AstraZeneca.
Publisher Figshare
DOI 10.6084/m9.figshare.1292883
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