What exactly is N in cell culture and animal experiments?

In this observational meta-science study, we surveyed a random sample of published animal experiments from 2011 to 2016 where interventions were applied to parents but effects examined in the offspring. We assessed whether entity–intervention pairs that contributed to the sample size (N) constituted true replication or pseudo replication. We found that only 22% of studies replicated the correct entity–intervention pair.

Creator(s) Marcus Munafo
Contributor(s) Charlie Clarke-Williams, Stan Lazic
Publication date 06 Sep 2017
Language eng
Publisher University of Bristol
Licence Non-Commercial Government Licence for public sector information
DOI 10.5523/bris.2uad9gecss2r2ksaujt85gj4a
Complete download (zip) https://data.bris.ac.uk/datasets/2uad9gecss2r2ksaujt85gj4a/2uad9gecss2r2ksaujt85gj4a.zip
Citation Marcus Munafo (2017): What exactly is N in cell culture and animal experiments?. https://doi.org/10.5523/bris.2uad9gecss2r2ksaujt85gj4a
Total size 5.8 KiB

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